Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that affects the central nervous system. It is characterized by a loss of dopamine-producing neurons in the substantia nigra region of the brain, leading to a range of motor and non-motor symptoms.
The symptoms of Parkinson's disease tend to worsen over time, and it is important for individuals with PD and their caregivers to be aware of the signs that the disease is progressing. In this response, we will discuss the signs that Parkinson's is getting worse.
Increased Tremors:
Tremors are one of the most common symptoms of Parkinson's disease, and they tend to worsen as the disease progresses. The tremors typically begin in one hand and then spread to the other hand and other parts of the body. As Parkinson's progresses, the tremors may become more severe and occur more frequently, making it difficult for individuals to perform daily activities.
Slowed Movement:
Another hallmark symptom of Parkinson's disease is bradykinesia, or slowed movement. This can make it difficult for individuals to perform simple tasks, such as getting dressed or brushing their teeth. As Parkinson's progresses, the slowness of movement may become more pronounced, and individuals may experience freezing episodes, where they suddenly become unable to move.
Difficulty with Balance and Coordination:
Parkinson's disease can also affect balance and coordination, making it difficult for individuals to walk or maintain their balance. As the disease progresses, individuals may experience more frequent falls and may require the use of mobility aids, such as a cane or walker.
Increased Rigidity:
Parkinson's disease can also cause rigidity in the muscles, which can make movement more difficult. As the disease progresses, the rigidity may become more severe, making it difficult for individuals to perform daily tasks.
Speech and Swallowing Difficulties:
Parkinson's disease can affect the muscles used for speaking and swallowing, leading to speech difficulties and an increased risk of choking. As the disease progresses, these symptoms may become more severe, making it difficult for individuals to communicate and eat.
Cognitive Changes:
Parkinson's disease can also cause cognitive changes, such as difficulty with memory, concentration, and decision-making. As the disease progresses, these changes may become more severe, and individuals may experience dementia.
Mood and Behavioral Changes:
Parkinson's disease can also cause mood and behavioral changes, such as depression, anxiety, and apathy. As the disease progresses, these symptoms may become more pronounced, and individuals may require treatment with medications or therapy.
Medication Effectiveness:
Parkinson's disease is typically treated with medications that increase dopamine levels in the brain. As the disease progresses, individuals may require higher doses of medication or may need to switch to different medications to maintain symptom control.
Increased Fatigue:
Parkinson's disease can cause fatigue, which can make it difficult for individuals to perform daily activities. As the disease progresses, fatigue may become more pronounced, and individuals may need to conserve their energy for essential tasks.
Sleep Disturbances:
Parkinson's disease can also cause sleep disturbances, such as difficulty falling asleep, staying asleep, or experiencing vivid dreams. As the disease progresses, these symptoms may become more severe, leading to daytime sleepiness and a decreased quality of life.
In conclusion, Parkinson's disease is a chronic and progressive neurodegenerative disorder that can lead to a range of motor and non-motor symptoms. The signs that Parkinson's is getting worse can include increased tremors, slowed movement, difficulty with balance and coordination, increased rigidity, speech and swallowing difficulties, cognitive changes, mood and behavioral changes, medication effectiveness, increased fatigue, and sleep disturbances.